Dictionary of Human Evolution and Biology

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Creutzfeldt-Jakob Disease, New Variant

Fatal degenerative disease of the human brain, sporadic and nonfamilial, now recognized as one of the transmissible spongiform encephalopathies (TSEs). In March 1996 a new variant of CJD in Great Britain was linked to exposure through the consumption of beef infected with bovine spongiform encephalopathy, or mad cow disease. About 85% of all CJD cases are now recognized as nvCJD and are associated with methionine homozygosity in the prion protein.

See Creutzfeldt-Jakob disease, familial, and Creutzfeldt-Jakob disease, sporadic.

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