Dictionary of Human Evolution and Biology

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DNA Hybridization

Process during which one single strand of DNA is bonded to its complementary sequence. With this technique, double-stranded DNA is thermally dissociated, creating the potential for single strands from two different species to bond in vitro, forming a hybrid DNA molecule. Evolutionary relationships can be deduced from the number of mismatched base pairs remaining in the hybrid DNA. Aka DNA-DNA hybridization.

See evolutionary conservation.

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