Dictionary of Human Evolution and Biology

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HLA Disease Associations

Nonrandom correlation of human immune-response antigens of the HLA complex with certain diseases, either causal or coincidental. The HLA B7 antigen, for example, is associated with malignant melanoma; B27 with ankylosing spondylitis; and B47 with congenital adrenal hyperplasia. The HLA DR3 antigen is associated with several diseases.

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