Dictionary of Human Evolution and Biology

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XY Homology

Mammalian X chromosome and counterpart, the Y chromosome, are homologous in certain regions, primarily in the distal portion of the long arms, where synapsis and crossing over. Genes in this pseudoautosomal region do not exhibit sexlinked inheritance. The major portion of the Y chromosome, once homologous to the X, was inverted in its early evolutionary history.

See nonrecombining region of the human Y chromosome.

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