Dictionary of Human Evolution and Biology

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Form of gigantism often confused with several similar disorders of which acromegaly is a feature; it is genetically heterogenous. Familial acromegaly is characterized by continued growth after a normal adolescent growth spurt, resulting in coarseness of features, and is due to overproduction of human growth hormone (hGH) secondary in the majority of cases to an hGH-secreting pituitary adenoma (aka familial somatotrophinoma). This condition is also obvious in skeletal remains; see paleopathology.

Cf. gigantism.

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