Dictionary of Human Evolution and Biology

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Amyotrophic Lateral Sclerosis, Familial

An autosomal dominant neurological condition characterized by an asymmetrical, progressive deterioration of cells in the brain stem and spinal cord; paralysis and death are inevitable. Manifests by the fifth decade of life. The defective gene is SOD1 (superoxide dismutase 1); Aka Lou Gehrig’s disease.

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