Dictionary of Human Evolution and Biology

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Chromosome Theory Of Cancer

Theory that cancer is caused by abnormal chromosomes that result from chromosomal mutations that occur during mitosis, attributed to German cytologist Theodor Boveri (1862-1915). Although the discovery of the Philadelphia chromosome in 1960 lent some support to this hypothesis, recent efforts to identify the causes of cancer have focused on mutations in DNA such as the p53 tumor supressor gene.

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