Dictionary of Human Evolution and Biology

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Disaccharide Intolerance Type I

Fermentation of accumulated sugars by bacteria results in symptomatic abdominal gas and painful, explosive diarrhea due to inability to absorb glucose and fructose after sucrose reduction; the cause is a mutation in the sucrase gene, an autosomal recessive. Aka sucrase deficiency, sucrose intolerance, los of sucraseisomaltase activity. One of several types (I, II, etc.); all have in common an inability to process the complex sugars lactose (see type III below), maltose, or sucrose, due respectively to lactase deficiency, maltase deficiency, or sucrase deficiency.

Cf. fructose intolerance and glucose-galactose malabsorption.

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