Dictionary of Human Evolution and Biology

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Duplication

1. in DNA, the addition of one or more base pairs from a sequence.

See DNA replication.

2. structural change that results in doubling of a portion of a chromosome, i.e. gene duplications within a linkage group. Chromosome duplications are sometimes caused by misalignment of homologous pairs during meiosis. DNA can occasionally be duplicated in other, nonhomologous chromosomes.

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