Dictionary of Human Evolution and Biology

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Gene Conversion

1. result of a rare error during DNA repair in meiotic prophase of a heterozygote that eliminates one of the four cistrons present; if a nonsister strand is used as a template, the result is three copies of one allele and only one of the other, instead of the normal count of two each.

2. form of nonreciprocal recombination in which one DNA sequence alters another, resulting in the conversion of one allele to another in a polymorphic set; biased conversion favors one allele over another; see back mutation.

3. see ectopic gene conversion.

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