Dictionary of Human Evolution and Biology

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Ghrelin

So-called hunger hormone; a 28-amino acid protein secreted cyclically by the stomach that acts as a hormone and is involved in the regulation of appetite and energy expenditure. Ghrelin stimulates the pituitary to secrete human growth hormone and seems to have an antagonistic relationship with leptin in feeding regulation. Ghrelin concentration also influences blood pressure and blood sugar concentration, insulin metabolism, and cardiac efficiency. The gene for ghrelin maps to HSA 3p26-p25.

See orexin(s).

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