Group of recessive familial lysosomal storage diseases
characterized by abnormal glycogen metabolism
involve the liver and muscles
. About 10 heritable forms
are known (0-IX), e.g.
Andersen (IV), AntopolDanon (IIb), Forbes-Cori (III), Hers (VI), McArdle (V), Pompe (II), Tarui (VII), and Von Gierke (I) disease
. Various enzymes
in the glycolysis pathway
are affected. Individually, each is rare; cumulatively, their incidence
is roughly 1: 20 000.
See carbohydrate metabolism