Dictionary of Human Evolution and Biology

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Hemophilia A

One of several inherited blood disorders caused by failure of one component of the normal blood-clotting system (factor VIII, an X-linked recessive). HEMA is characterized by spontaneous, unchecked bleeding into large joints and muscles, easy bruising, poor blood clotting, hematomas and chronic arthritis; fatal if untreated. HEMA is the best-known form of hemophilia (the royal hemophilia), accounting for 80% of all coagulation disorders.

Cf. hemophilia B.

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