Dictionary of Human Evolution and Biology

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Hypertrichosis, Congenital Generalized (CGH, HTC2)

Rare congenital condition characterized by an increase in the number of hair follicles in locations such as the face and upper body, resulting in profound hirsutism; has been called an atavism (a reactivated ancestral DNA sequence). The mutation is in an X-linked dominant gene, HTC2. Aka the wolf man syndrome. Related conditions include hypertrichosis universalis, and congenital generalized hypertrichosis with gingival hyperplasia.

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