Dictionary of Human Evolution and Biology

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Immunological Diffusion Test

Test for genealogical affinity in which antisera from one species reacts to antigens from another species on an immunodiffusion plate in vitro, and the amount of resulting precipitate is scored visually, exploiting the empirical observation that closely related individuals produce less precipitate. M. Goodman applied this test to many animals beginning in 1962, and was thus one of the first to produce a molecular phylogeny of mammals, including the primates.

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