Dictionary of Human Evolution and Biology

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Luteinizing Hormone

1. glycoprotein gonadotropic substance secreted by the anterior pituitary gland; acts with follicle-stimulating hormone to promote ovulation as well as secretion of androgens and progesterone. LH instigates and maintains the secretory phase of the mammalian estrus and menstrual cycles. In females, it is concerned with formation of the corpus luteum and in males, it stimulates the development and functional activity of testicular Leydig cells to secrete testosterone and stimulates the interstitial cells of the testis, resulting in spermatogenesis. Aka Aschheim-Zondek hormone, interstitial cell-stimulating hormone (ICSH), luteotropin, lactogenic hormone.

See gonadotropinreleasing hormone.

2. a recombinant (genetically engineered) gene product of the same name.

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