Dictionary of Human Evolution and Biology

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Protein found in most eukaryotic cells; two classes exist. Myosin I (cytoplasmic myosin) is involved in development and cell locomotion. Myosin II (muscle myosin) acts as both a structural protein and an enzyme, and is involved in muscle contraction by interacting with actin (forming actomyosin) to convert energy stored in ATP. Numerous isoforms of myosin are known to exist, and are coded for by at least ten genes; many of the isoforms are generated by alternative splicing. One of these isoform variants (myosin heavy chain 16) is inactivated in humans, but active in other primates and a variety of vertebrates.

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