Dictionary of Human Evolution and Biology

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Pellagra

Rough skin; a state of malnutrition caused by a reversible deficiency (avitaminosis) of the vitamin niacin. The symptoms include apathy, followed by dermatitis (skin lesions), diarrhea, dementia, and death. Niacin is required (with coenzymes) for the reduction of sugars. Classic pellagrins are also deficient in thiamine, riboflavin, and folic acid. Pellagra is common where maize (which is deficient in niacin) is a dietary staple, and also among alcoholics. Aka Lombardy leprosy and maidism.

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