Dictionary of Human Evolution and Biology

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Prion Protein

Protein identified c. 1996, when a new variant of Creutzfeldt-Jakob disease in Great Britain was linked to exposure through the consumption of beef and dairy cattle infected with bovine spongiform encephalopathy (BSE, aka mad cow disease). New variant CJD is one of the transmissible spongiform encephalopathies. Native prion protein exists in the human CNS, and increases in those tissues with age.

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