Dictionary of Human Evolution and Biology

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Situs Inversus Viscerum

Failure to establish normal left-right asymmetry during embryonic development results in heterotaxy (reversed asymmetry); the usual case is a complete mirror image of normal internal visceral orientation, with the heart in the right lung cavity, etc. Most cases are familial and segregate as an autosomal recessive, although X-linked forms have been reported. There is suspicion of a paternal age effect.

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